Description

Velpanat is an combination of velpatasvir 100mg+ Sofosbuvir 400mg. Velpanat is a two-drug combination for the treatment of hepatitis C. It is administered as a single daily pill containing the viral NS5A inhibitor velpatasvir and sofosbuvir,a nucleotide inhibitor of the viral RNA polymerase. It is the first treatment, that works for all genotypic, and is taken entirely by mouth. A single tablet regimen is used for adults with genotype 1-6 chronic hepatitis C virus (HCV) infection with pangenotypic activity. Dosage and Administration: Take Velpanat exactly as your healthcare provider tells you to. Patients without cirrhosis or with compensated cirrhosis (Child-Pugh A): velasof for 12 weeks. Patients with decompensated cirrhosis (Child-Pugh B or C): velasof. plus weight-based ribavirin with food for 12 weeks Weight-based ribavirin dose. Less than 75 kg: 1000 mg/day PO divided BID ≥75 kg: 1200 mg/day PO divided BID Ribavirin starting dose and on-treatment dosage should be modified based on hemoglobin and creatinine clearance Dose modification:Severe renal impairment (eGFR less than 30mL/min/1.73 m²) or ESRD: No dosage recommendation can be give owing to higher exposures (up to 20-fold) of the predominant sofosbuvir metabolite Side effects: The most common adverse reactions with velpatasvir were headache and fatigue and when used with RBV in decompensated cirrhotics were fatigue, anemia, nausea, headache, insomnia, and diarrhea. Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects. storage: Velpanat Store below 30°C (86 ºF). Brand name : Velpanat Active Ingeridents : Velpatasvir Sofosbuvir Company Name : Natco Package : 28 tablets/bottle Strength : Velpatasvir 100Mg Sofosbuvir 400Mg